Greenburg has been married three times. His first wife was writer Nora Ephron; their marriage ended in divorce after six years. His second wife, from 1980-1998, was reporter Suzanne O'Malley, who wrote a series of articles on the Andrea Yates case, later resulting in her book, Are You There Alone: The Unspeakable Crime of Andrea Yates (2004). Before their divorce, Greenburg and O'Malley had a son, Zack O'Malley Greenburg, after whom his father named his best-selling series of children's books. Zack played the title role of Lorenzo in the film Lorenzo's Oil. Greenburg is currently married to Judith C. Wilson, who as J.C. Greenburg writes children's books.

For adults

• How to Be a Jewish Mother: A Very Lovely Training Manual (1964)
• Kiss My Firm But Pliant Lips (1965)
• How to Make Yourself Miserable: Another Vital Training Manual (1966)
• Chewsday (1968)
• Philly: A Novel (1969)
• The Shame of Our Art Museums (1969)
• Scoring (1972)
• Something's There: My Adventures in the Occult (1976)
• Love Kills (1978)
• What Do Women Want? (1982)
• How to Avoid Love and Marriage: Guaranteed to Ruin Any Deep Relationship or Your Money Back (1983)
• Confessions of a Pregnant Father (1986)
• Exes (1990)
• Moses Supposes: The Bible As Told to Dan Greenburg (1997)

For children

• The Zack Files (series)
• Secrets of Dripping Fang (series)
• Maximum Boy (series)
• Weird Planet (series)
• Jumbo the Boy and Arnold the Elephant
• The Bed That Ran Away from Home
• Young Santa
• Claws

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