David Hopkins first professional writing was after college in 2002. Aja Jones asked him to write a stage play for her theatre troupe to be performed at the University of Texas at Arlington. The only performance of "Space to Occupy" was on September 14, 2002. Immediately afterwards, Hopkins began writing comics.

The first year, Hopkins wrote a five issue series The Insight. Set in Dallas, Hopkins used extensive photo references from actual locations in the city. (He would later do this for Karma Incorporated, which also takes place in Dallas.) Over the course of two years, there were two different artists attached to the project, which never came together and remains unpublished.

In June 2003, Hopkins wrote a 144 page graphic novel Astronaut Dad -- a fictional story about three astronaut families living in Houston, set in 1963. Hopkins cites this work as his "most personally satisfying". It is set to be published by Silent Devil Productions.

Later that year, encouraged by the Isotope Awards, Hopkins self-published a mini-comic "Some Other Day"[1] with artist Brian Kelly.

In 2004, Hopkins' first published work was a short story in Viper Comics Dead@17: Rough Cut[2]. Creator Josh Howard invited him to contribute to this anthology. Afterwards, he also wrote short stories for Western Tales of Terror[3], Silent Forest Television Parody Special[4], and Dead@17: Rough Cut Volume 2.

At Comic Con International in 2005, Viper Comics released Hopkins first series Karma Incorporated, illustrated by Tom Kurzanski and colored by Marlena Hall. In addition to the standard blue cover of issue one, a red exclusive variant cover was printed as part of the Diamond Distributors exclusives for that year. A second series was approved, but never completed.

Hopkins wrote Emily Edison, which was published by Viper Comics in 2006, and illustrated by Brock Rizy. It was released as a trade paperback. That summer, Rizy and Hopkins went on a month long book tour to promote the release through California, Texas, Oklahoma, and Kansas.

David Hopkins is also an English III and Creative Writing teacher at Martin High School in Arlington, Texas.