Book Reviews of Deadly Medicine: Why Tens of Thousands of Heart Patients Died in America's Worst Drug Disaster

Deadly Medicine: Why Tens of Thousands of Heart Patients Died in America's Worst Drug Disaster
Deadly Medicine Why Tens of Thousands of Heart Patients Died in America's Worst Drug Disaster
Author: Thomas Moore
ISBN-13: 9780684804170
ISBN-10: 0684804174
Publication Date: 3/1/1995
Pages: 352
Rating:
  • Currently 5/5 Stars.
 1

5 stars, based on 1 rating
Publisher: Simon & Schuster
Book Type: Hardcover
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This is an excellent account of the effects of allowing marketing of Tamnbocor (flecainide) as an anti-arrhythmic based on "surrogate" intermediate endpoints. Later there was recognition that in fact the drug was associated with increased cardiac death rates when a "gold standard" randomized controlled trial was undertaken. It also shows the problematic relationships between the payment and support of academic researchers into drug effectiveness and the drug firms, many of whose products have been life saving and life transforming. A very well balanced book and very enjoyable reading.