There was a young adult book I read back in the mid- to late-nineties.  It was about a teenager that had ESP.  She temporarily (or maybe it was permanently?) lived in a hotel.  I think she had a grandmother who was a major character in the book as well.  I can't remember if the grandma had ESP too. 

This is all I can remember about the book, but it has been bothering me for a while now.  If anyone knows what I'm talking about, it would be a big help!

The Juniper Game?

^ No, but thanks for your help!

A Gift of Magic by Lois Duncan?

^Thanks, that might be it!  I did some more research and thought that also it might be The Girl with the Silver Eyes by Willo Davis Roberts.  I think I'm mixing those two up.  I guess I"ll get them both and re-read them! 

Thanks for the help! 

It's definitely the Girl With The Silver Eyes.