Early years

La Mettrie was born at Saint-Malo in Brittany on December 25, 1709 and was the son of a prosperous textile merchant. His initial schooling took place in the colleges of Coutances and Caen. After attending the Collège du Plessis in Paris, he seems to have acquired a vocational interest in becoming a clergyman, but after studying theology in the Jansenist schools for some years, his interests turned away from the Church. In 1725, La Mettrie entered the College d'Harcourt to study philosophy and natural science, probably graduating around 1727. At this time, d'Harcourt was pioneering the teaching of Cartesianism in France.

Medical career

After his studies at d'Harcourt, La Mettrie decided to take up the profession of medicine. A friend of the La Mettrie family, François-Joseph Hunauld, who was about to take the chair of anatomy at the Jardin du Roi, seems to have influenced him in this decision. For five years, La Mettrie studied at faculty of medicine in Paris, and enjoyed the mentorship of Hunauld.

In 1733, however, he departed for Leiden to study under the famous Herman Boerhaave. His stay in Holland proved to be short but influential. In the following years, La Mettrie settled down to professional medical practice in his home region of Saint-Malo, disseminating the works and theories of Boerhaave through the publication and translation of several works. He married in 1739 but the marriage, which produced two children, proved an unhappy one. In 1742, La Mettrie left his family and travelled to Paris, where he obtained the appointment of surgeon to the Gardes Francaises regiment, taking part in several battles during the War of the Austrian Succession. This experience would instill in him a deep aversion to violence which is evident in his philosophical writings. Much of his time, however, was spent in Paris, and it is likely that during this time he made the acquaintance of Maupertuis and the Marquise de Chatelet.

It was in these years, during an attack of fever, that he made observations on himself with reference to the action of quickened blood circulation upon thought, which led him to the conclusion that mental processes were to be accounted for as the effects of organic changes in the brain and nervous system. This conclusion he worked out in his earliest philosophical work, the Histoire naturelle de l'âme (1745). So great was the outcry caused by its publication that La Mettrie was forced to quit his position with the French Guards, taking refuge in Leiden, where he developed his doctrines still more boldly and completely in L'Homme machine a hastily-written treatise based upon consistently materialistic and quasi-atheistic principles. La Mettrie's materialism was in many ways the product of his medical concerns, drawing on the work of 17th-century predecessors such as the Epicurean physician Guillaume Lamy.

The ethical implications of these principles would later be worked out in his Discours sur le bonheur, that book La Mettrie considered his Magnum opus. Here he developed his theory of remorse, i.e. his view about the inauspicious effects of the feelings of guilt acquired at early age during the process of enculturation. This was the idea which brought him the enmity of virtually all thinkers of the French enlightenment, and a Damnatio memoriae which was lifted only a century later by Friedrich Albert Lange in his Geschichte des Materialismus.

Flight to Prussia

La Mettrie's hedonistic and materialistic principles caused outrage even in the relatively tolerant Netherlands. So strong was the feeling against him that in 1748 he was compelled to leave for Berlin, where, thanks in part to the offices of Maupertuis, the Prussian king Frederick the Great not only allowed him to practise as a physician, but appointed him court reader. There La Mettrie wrote the Discours sur le bonheur (1748), which appalled leading Enlightenment thinkers such as Voltaire, Diderot and D'Holbach due to its explicitly hedonistic sensualist principles which prioritised the unbridled pursuit of pleasure above all other things.

Death

La Mettrie's celebration of sensual pleasure was said to have resulted in his early death. The French ambassador to Prussia, Tirconnel, grateful to La Mettrie for curing him of an illness, held a feast in his honour. It was claimed that La Mettrie wanted to show either his power of gluttony or his strong constitution by devouring a large quantity of pâte de faisan aux truffes. As a result, he developed a gastronomic illness of some sort, became delirious, and died.

Frederick the Great gave the funeral oration, which remains the major biographical source on La Mettrie's life. He declared, "La Mettrie died in the house of Milord Tirconnel, the French plenipotentiary, whom he had restored to life. It seems that the disease, knowing with whom it had to deal, was cunning enough to attack him first by the brain, in order to destroy him the more surely. A violent fever with fierce delirium came on. The invalid was obliged to have recourse to the science of his colleagues, but he failed to find the succor that his own skill had so often afforded as well to himself as to the public."[1] However, in a confidential letter to the Markgräfin von Bayreuth, Frederick wrote "He was merry, a good devil, a good doctor, and a very bad author. By not reading his books, one can be very content." He then mentioned that La Mettrie had indigestion from pheasant paste. The reason of his early death has never been disclosed. He was survived by a 5 year old daughter and his wife.

La Mettrie's collected Oeuvres philosophiques appeared after his death in several editions, published in London, Berlin and Amsterdam respectively.