A native of France, Mireille Guiliano grew up in Rombas, Lorraine amidst cooks, chefs, and restaurateurs. Mireille completed her primary education as an exchange student in the United States (1966). She completed her secondary education in Paris, where she studied French and English literature at the Sorbonne Nouvelle (1966—1970) and received her Master's degree. She also attended the Institut Supérieur d'Interprétariat et de Traduction where she received a certification as a translator/interpreter.

Prior to becoming a full-time author, Mireille was for over 20 years the spokesperson for Champagne Veuve Clicquot and a senior executive at LVMH as well as CEO of Clicquot, Inc., the United States firm she helped found in 1984 and was its first employee.

Mireille Guiliano is one of the few women to rise to the top of the luxury industry and is well-known for her business success. Under her leadership, Veuve Cliquot grew its U.S. marketshare from less than 1% to 25%.After publishing French Women Don’t Get Fat and French Women for All Seasons, Guiliano decided to retire from Cliquot, Inc. (LVMH) and follow her new passion to become a full-time writer.

Mireille currently resides in Manhattan with her husband, Edward, president and CEO of the New York Institute of Technology, and makes frequent trips to their homes in Paris and Provence for business and pleasure.

Mireille Guiliano's first book, French Women Don't Get Fat: The Secret of Eating for Pleasure was a #1 bestseller in the US, as well as a best seller in many other countries. In less than six months, well over 1 million copies of the book were printed and it has been translated into 37 languages. The book was based on her gaining weight as a teen. Her family physician, dubbed by Guiliano as "Dr. Miracle," came to the rescue. Reintroducing her to classic principles of French gastronomy plus time-honored tricks of the local women, he helped restore her shape with a fresh understanding of food, drink, and living.

In the fall of 2006, Mireille followed up with French Women for All Seasons: A Year of Secrets, Recipes and Pleasure. Devoted to l'art de vivre (the art of living), the book contains 100 additional recipes that feature French staples such as leeks and chocolate. While her first book enabled readers to enjoy a healthier relationship with food, French Women for All Seasons sought to enable readers to enjoy a healthier relationship with life. In both, through her personal stories and illustrations, she espouses living life to the fullest by embracing quality, sensitivity, seasonality, and pleasure while maintaining a healthy equilibrium.

In Fall 2009, Atria Books published Guiliano's third book, Women, Work & The Art of Savoir Faire. The book is a guide for women in business, exploring issues of balancing career and personal life, risk taking, career advancement, leadership, branding, etiquette, mentoring, communication skills, and personal relationships. It draws on the insights and experiences Guiliano garnered over her thirty-year career in business, including a long stop as CEO of Clicquot, Inc. (LVMH). As in her other books, Guiliano leads with the message that life, even in business, should be a pursuit of pleasure.