Suspicion of Guilt focuses on Denni Mahoney. Denni runs a home for girls who have just left the foster care program and entered young adulthood. She helps them find employment, take college classes and prepare to function independently in the real world, but someone doesn't like what she is doing. Flooded basements, fires in the kitchen, and missing items are just a few of the not-so-subtle hints he or she is leaving. Denni is determined to move forward ignoring the warnings, but Detective Reece Corrigan has other plans. Reece is determined to get to the bottom of the attacks even if that means suspecting one of the girls in the home.