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Botulism, anthrax, smallpox, plague: as medical producer for television's highly-rated morning news program, Annabelle Murphy makes her living explaining horrific conditions to the nation. So when a KEY News colleague dies with symptoms terrifyingly similar to those of anthrax, she knows the panic spreading through the corridors of the Broadcast Center is justified.

As one death follows another, Annabelle's co-workers look to her for assurance, but she finds it hard to give comfort. To her, the circumstances surrounding the infections suggest diabolical murders.

And when the authorities lock down the Broadcast Center with the identity of the killer still unknown, neither the victims nor the murderer can escape...