Lamott was born in San Francisco, and is a graduate of Drew School. Her father, Kenneth Lamott, was also a writer. His death was the focus of her first published novel Hard Laughter. She has one son, Sam, who was born in 1989 and a grandson, Jax.

Lamott's life was documented in Freida Lee Mock's 1999 documentary Bird by Bird with Annie: A Film Portrait of Writer Anne Lamott. Because of the documentary and her following on Facebook and other online networks, she is often called the "People's Author".

Lamott has described why she writes: "I try to write the books I would love to come upon, that are honest, concerned with real lives, human hearts, spiritual transformation, families, secrets, wonder, craziness...and that can make me laugh. When I am reading a book like this, I feel rich and profoundly relieved to be in the presence of someone who will share the truth with me, and throw the lights on a little, and I try to write these kinds of books. Books, for me, are medicine." Lamott is cited as a writer who captures well the style of narrative nonfiction called particularism, coined by Howard Freeman.

Novels

Non-fiction