Active in fandom before he broke into professional comics at Marvel Comics in 2003, Reese was one of the pioneers in the field of Internet-based Fan Fiction. Reese founded the MV1talk mailing list in April 1998, the first known mailing list devoted to fans of a shared continuity fan fiction group. Reese was a part of a number of influential comic-based fan fic groups including Marvel Volume One, Avengers 2000, Marvel-X and Marvel 2000.

In 2003 Reese began work for Marvel Comics on volume five of their Marvel Encyclopedia series. Reese was responsible for handling the Blade and Ghost Rider sections of the book. Following this, Reese worked on both the ongoing The Official Handbook of the Marvel Universe series and on D6 Space: Fires of Amatsumara Worldbook for West End Games. Amongst the issues of the Handbook that Reese worked on were Marvel Legacy: 1960s, Marvel Legacy: 1970s, Spider-Man 2006, Teams 2006, A-Z volumes 1-7 and Horror 2006. Reese also contributed to the New Avengers: Most Wanted and Marvel Monsters: From the Files of Ulysses Bloodstone books.

Reese then contributed to USER'S Most Wanted, a villains supplement for the Godsend Agenda game belonging to Khepera Publishing. USER'S Most Wanted was published in May 2007.

Reese's first novel Conquerors of Shadow: The Adventures of Eobard Grace was published in 2005, featuring a setting and character inspired by the works of Edgar Rice Burroughs. This work was followed by Lucifer's Cage and a sequel entitled Kingdom of Blood. These last two novels feature the adventures of a 1930s era masked vigilante dubbed the Rook and were inspired by the pulp magazine heroes of the past. There are elements that relate back to the Conquerors of Shadow novel, forming a shared universe. Covers for the Eobard Grace book as well as Lucifer's Cage and Kingdom of Blood were by artist Cari Reese.

A collection of Rook stories was released in early 2008, reprinting the two previous Rook novels with three new short stories: "The Gasping Death," "The Black Mass," and "Abominations." This collection was published by Wild Cat Books under the title The Rook Volume One. Both Lucifer's Cage and Kingdom of Blood went out of print in late 2008 to avoid confusion in the marketplace.

A second collection entitled The Rook Volume Two was released in October 2008, with cover art by Frank Brunner. The stories contained in volume two are "Kazlov's Fire," "Blitzkrieg," "Bloodwerks," "The Gorgon Conspiracy," "The Shambling Ones," and "Origins."

A standalone e-book novella entitled "The Bleeding Hells" was released in February 2008, pairing the Rook with public domain pulp characters Doctor Satan, Ascott Keane and the Black Bat. "The Bleeding Hells" was reprinted in The Rook Volume Three, released in January 2009. Volume three featured cover and interior artwork by comics artist Anthony Castrillo. Wild Cat Books published volume four in September 2009, featuring cover artwork by Norm Breyfogle. The fifth volume was released in October 2010.

Reese has also written stories for several anthologies published by Wild Cat Books. Two stories featuring a character named Grimarr were published in Tales of the Norse Gods and a story starring the public domain hero the Black Terror saw print in Legends of the Golden Age. As part of Wild Cat's new line of digest-sized pulp adventures, Reese's Guan-Yin and the Horrors of Skull Island novella, a supernatural pirate story, was published in February 2009. June 2009 saw the release of Savage Tales of Ki-Gor, Lord of the Jungle, another in Wild Cat Books' line of Pulse Pounders, featuring two of Reese's stories -- "The Ivory Goddess" and "The Devil's Domain."

In January 2010, Wild Cat Books released Rabbit Heart, a slasher horror novel with pulp underpinnings. This was the first work in Reese's career to be labeled "For Mature Readers." Rabbit Heart is set entirely in Reese's hometown of Milledgeville, Georgia. In March 2010, Reese's short story, "Sins of the Past," was published in the anthology How the West Was Weird from Pulpwork Press.

The Rook Series

• The Rook: Volume One (2008)
• The Rook: The Bleeding Hells (2008) - e-book only release
• The Rook: Volume Two (2008)
• The Rook: Volume Three (2009)
• The Rook: Volume Four (2009)
• The Rook: Volume Five (2010)

Miscellaneous Fiction

• The Conquerors of Shadow (2005)
• Legends of the Golden Age (2008)
• Tales of the Norse Gods (2009)
• Guan-Yin and the Horrors of Skull Island (2009)
• Savage Tales of Ki-Gor, Lord of the Jungle (2009)
• 818 (2009) - Reprints Guan-Yin and the Horrors of Skull Island as part of a larger anthology
• Rabbit Heart (2010)
• How the West Was Weird (2010)

Marvel Comics Work

• Marvel Encyclopedia Vol. 5: The Marvel Knights (2004)
• Marvel Knights 2005 (2005)
• Spider-Man 2005 (2005)
• Ultimate Universe 2005 (2005)
• Horror 2005 (2005)
• Teams 2005 (2005)
• Marvel Monsters: From the Files of Ulyssess Bloodstone (2005)
• New Avengers: Most Wanted (2005)
• All-New Official Handbook of the Marvel Universe (2006) - issues 1-7
• Marvel Legacy: The 1960s (2006)
• Marvel Legacy: The 1970s (2006)
• Marvel Legacy: The 1980s (2006)
• Marvel Monsters Hardcover (2006) - reprints the work from Marvel Monsters: From the Files of Ulyssess Bloodstone
• Ghost Rider: Finale (2007) - reprints the Dan Ketch entry from Marvel Knights 2006
• Marvel Legacy: The 1960s-1990s Handbook (2007) - reprints the individual 1960s, 1970s and 1980s volumes in a trade paperback format
• All-New Official Handbook Of The Marvel Universe A To Z (2008) - reprints the individual entries from the various Official Handbook oneshots and A-Z series

Roleplaying Game Work

• D6 Space: The Fires of Amatsumara (2006)
• Godsend Agenda: USER's Most Wanted (2007)

Miscellaneous Nonfiction

• History of the Baldwin County Public Library (2008)