Drogin was born prematurely and weighed only 3 pounds, 7 ounces. She and her younger brother were raised in Spring Valley, New York. She attended Brandeis University, where she met her husband. She later attended Boston University School of Law, and earned her law degree from New York University. Drogin passed the New York State Bar Exam in 1991, and was sworn in at the same time as John F. Kennedy, Jr. Although she enjoyed law school, she realized quickly that she did not enjoy practicing law. After the birth of her first child in 1992, Drogin became a stay-at-home mother and eventually decided to try writing. It took seven years, during which time she completed ten books, but in 1998 she finally sold a novel to Harlequin for their Temptation Line. In 2002 Drogin's first single-title novel, The Bachelor, was selected a book pick for Kelly Ripa's "Reading With Ripa" book club. This big break allowed the book to rise as high as number four on the New York Times Bestseller List (tied with a book by fellow romance novelist Nora Roberts).
Drogin promotes awareness for Susan G. Komen for the Cure, the Humane Society, and the American Heart Association. She is a huge fan of the New York Mets and the Boston Red Sox.