Genetics and Genomics in Medicine Author:Tom Strachan, Judith Goodship, Patrick Chinnery This new textbook explains the science behind the uses of genetics and genomics in medicine today. It is not just about rare inherited and chromosomal disorders, but how genetics affects the whole spectrum of human health and disease. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genet... more »ic information in medicine and are indicating the role of genetics in common diseases. Other new advances, such as the role of epigenetics and non-coding RNA are given in-depth coverage. The discussion on genetic approaches to treatment includes pharmacogenomics and the prospects for personalized medicine. Cancers are essentially genetic diseases and are given a dedicated chapter that includes new insights from cancer genome sequencing. The final chapter on genetic testing and ethics also covers important developments in clinical and public health genomics. Clinical disorders are covered throughout and there are extensive end-of-chapter questions and problems.« less