Mukasa was the son of Makabugo Sensalire, a minor chief in the Buddu District (present day Masaka District). He converted to Christianity at a young age. He suffered serious injury in the 1886 massacre of Christians by Mwanga II. As a result, he had a weak leg. Around 1898, he married ??nn?h W?w?muk?, the daughter of a former chief minister of Uganda.

Mukasa's book Uganda's Katikiro in England details his experiences on his journey from his homeland to the coronation of Edward VII of the United Kingdom. It was translated into English by Ernest Millar of the Church Mission Society in Uganda. In London, Mukasa stayed at Alexandra Palace, and visited the London Hippodrome, attended a play in Drury Lane, and met with a variety of people such as writer Henry Morton Stanley and ex-governor of Uganda Harry Johnston.

Notes

Sources