Meyer was born in the O'Fallon neighborhood in south St. Louis in 1943, and still speaks with a working-class south St. Louis accent. Her father went into the Army to fight in World War II soon after she was born. Meyer has said in interviews that he began molesting her upon his return. She often talks about her experience in her meetings.
A graduate of O'Fallon Technical High School in St. Louis, she married a part-time car salesman shortly after her senior year of high school. The marriage lasted five years. She maintains that he frequently cheated on her and persuaded her to steal payroll checks from her employer. They used the money to go on a vacation to California, she claims to have returned the money years later. After her divorce, Meyer frequented local bars before meeting Dave Meyer, an engineering draftsman. They were married on January 7, 1967.
Meyer also reports that she was praying intensely while driving to work one morning in 1976 when she said she heard God call her name. She had been born-again at age nine, but her unhappiness drove her deeper into her faith. She says that she came home later that day from a beauty appointment "full of liquid love" and was "drunk with the Spirit of God" (and presumably spoke in tongues) that night while at the local bowling alley.
- :I didn't have any knowledge. I didn't go to church. And I had a lot of problems, and I needed somebody to kind of help me along. And I think sometimes even people who want to serve God, if they have got so many problems that they don't think right and they don't act right and they don't behave right, they almost need somebody to take them by the hand and help lead them through the early years.
Meyer was briefly a member of Our Savior's Lutheran Church in St. Louis, a congregation of the Lutheran Church - Missouri Synod. She began leading an early-morning Bible class at a local cafeteria and became active in Life Christian Center, a charismatic church in Fenton. Within a few years, Meyer was the church's associate pastor. The church became one of the leading charismatic churches in the area, largely because of her popularity as a Bible teacher. She also began airing a daily 15-minute radio broadcast on a St. Louis radio station.
In 1985, Meyer resigned as associate pastor and founded her own ministry, initially called "Life in the Word". She began airing her radio show on six other stations from Chicago to Kansas City.
In 1993, her husband Dave suggested that they start a television ministry. Initially airing on superstation WGN-TV in Chicago and BET, her program, now called "Enjoying Everyday Life," is still on the air today.
In 2004 St. Louis Christian television station KNLC, operated by the Rev. Larry Rice of New Life Evangelistic Center, dropped Meyer's programming. Rice had been a longstanding Meyer supporter, but claimed that her "excessive lifestyle" and teachings which often go "beyond Scripture" were the impetus for canceling her program.
In 2005,
Time magazine's
25 Most Influential Evangelicals in America ranked Joyce Meyer as 17th.