Merck's 1899 Manual Author:Merck & Co. This facsimile of the first edition of The Merck Manual, published as Merck's 1899 Manual, has been produced in celebration of the 100th anniversary of this not-for-profit publication. The Merck Manual has been continuously published longer than any other general textbook of medicine in the English language. — We hope that you enjoy revisiting me... more »dical history through this facsimile edition. It illustrates the enormous advances in medical knowledge and practice that have taken place over the past 100 years.« less