Peggy Webb has born and raised on a farm in Lee County, Mississippi. As a child she would often sit in the hayloft and write down her stories. Her first publication came through her husband, the owner of a water well contracting business. As the secretary of the state trade organization, he was responsible for publishing a newsletter. Webb assisted him with the newsletter, and, to fill space, began a humor column. This was picked up in the late 1960s by two trade magazines, The Water Well Journal and Ground Water Age. Over two hundred of her columns were published.
In 1984, while writing her master's thesis at the University of Mississippi, Webb wrote her first romance novel. Her first novel was rejected because publishers thought it had too much comedy and not enough romance. Bantam Books purchased her second novel, Taming Maggie,, and, in order to complete the revisions Bantam required, Webb had to postpone the defense of her thesis. She did eventually receive her M.A. in fine arts, the same summer that her first novel was released. Taming Maggie, reached number one on the Waldenbooks bestseller list, earning her their award for Bestselling New Romance Author. With its success, Bantam rethought their rejection of Webb's first novel. After she made changes to further emphasize the romance, Bantam published the book as Birds of a Feather. This novel reached number two on the romance bestseller list, and is considered to be the first true comedic romance.
Webb currently writes for Harlequin and Silhouette. Her novels for them are published in approximately 17 languages. She is a five-time nominee for Romantic Times Reviewer's Choice Awards.