I am getting so many Similar to Wish e-mails it is driving me crazy I have some  of my wish list books listed as Large Print because of my eye sight.  And every time some one list a book that is not large print I get the e-mail. Hoping there is some way to block them

Yep, It's in your account under settings. Scroll down until you see "Email Settings" and choose what emails you do and do not want to receive. Don't forget to click the update button before you navigate away from the page.

thank you very much will do that now 

You can also block these emails for each individual ISBN that you're getting offered. I.e. if you only want large print and you are continually getting offered the regular hardcover and paperback versions, then click the links in the emails to block notification of those specific versions. You'll have to do it once for each alternate ISBN.

Bertie, I certainly understand why you might not want those e-mails if you are looking for the large print versions - they are hard to come by.  Me, I'm so happy with those e-mails, as on at least 3 occasions I was able to snap up a book I may have been waiting months for otherwise. 

I do love how  PBS has features that can work for so many different needs.  Your needs in this case - turn off those e-mails - and mine - gimme anything!