In 1986, Lynes along with John Crane, former assistant to Royal Rife and a group of investors including John Bedini incorporated as Rife Laboratories Inc. Lynes began publishing on the topic of alternative cancer treatments in
Cover Up, a regular newsletter as well as a growing number of books on the topic of Royal Rife.
The Cancer Cure That Worked was published in 1987 based on Lynes interviews with Crane.
After a dispute over ownership of a Rife microscope, John Crane filed a lawsuit on April 19, 1988 in the Superior Court of California against Lynes and other investors claiming they had conspired to steal the microscope from him.
Later editions of the
The Cancer Cure That Worked included a disclaimer by Lynes that rejected much of the fraudulent multi-level marketing of Rife machines which occurred after the publication of the book.
"Sadly, in most cases, the cancer patients lost precious time - three or four months - before recognising that they had been swindled in a clever marketing scheme. People died because they had faithfully used the worthless black box instead of orthodox or alternative, non-conventional cancer therapies which actually worked."—Barry Lynes