Bisphosphonates Author:Graham Russell, Stuart Ralston, Mike Rogers The development of bisphoshonates - synthetic analogues ofpyrophosphate, a naturally occurring substance - represents a major therapeutic advance. In this timely volume, the authors review the latest developments in this fascinating field, focusing on the cellular and molecular mechanisms of action of bisphosphonates, their current use and their... more » potential role in the prevention and treatment of osteoporosis.« less