Von Hoffman never went to college; he worked as a political organizer for the community activist Saul Alinsky; Ben Bradlee, then the editor of the Post, hired him from the Chicago Daily News.

He was said to have been a brilliant reporter, and wrote an incendiary column for the paper's Style section. In her memoirs, Katharine Graham, then the newspaper's publisher, wrote of him: “My life would have been a lot simpler had Nicholas von Hoffman not appeared in the paper.” She added, however, that "I firmly believed that he belonged at the Post."

Beginning in 1979 and continuing throughout the '80s, von Hoffman recorded more than 250 radio commentaries, audio op-eds in the sardonic style he used on 60 Minutes. These commentaries were broadcast on the nationally syndicated daily radio program, Byline, which was sponsored by the Cato Institute. Subjects of von Hoffman's audio op-eds included the 1984 Democratic primary candidates, the Reagan administration's foreign policy in Central America and the Middle East, and the cynical, self-serving misuse of language by politicians.

In 1988, fake presidential candidate Jack Tanner named von Hoffman as his pick for Chairman of the Federal Reserve Board in Robert Altman's HBO series Tanner '88.

Von Hoffman is the author of more than a dozen books, notably: Capitalist Fools: Tales of American Business, from Carnegie to Forbes to the Milken Gang (1992) and Citizen Cohn (1988), a biography of Roy Cohn, which was made into an HBO movie. A recent title is Hoax: Why Americans Are Suckered by White House Lies (2004).

Von Hoffman also wrote a libretto for Deborah Drattell's Nicholas and Alexandra for the Los Angeles Opera which was performed in the 2003/04 season under the direction of Plácido Domingo.

Currently he is a columnist for the New York Observer.

Von Hoffman was fired by Don Hewitt for calling then President Richard Nixon a dead mouse on America's kitchen floor. His collaborations, both literary and otherwise, with Doonesbury cartoonist Garry Trudeau are worth noting, in particular the 1976 book "Tales From the Margaret Mead Taproom." In this book he recounted his adventures in American Samoa with Trudeau and actress Elizabeth Ashley, as they and several others experienced life in the American territory, which Trudeau had lampooned in a series of "Doonesbury" strips involving Uncle Duke's adventures as the territory's appointed governor. He also writes for Architectural Digest.

He has three sons: Alexander, a noted historian; Aristodemus, who works in law-enforcement; and Constantine, also a journalist.

(partial list)

• The Multiversity: A Personal Report on What Happens to Today's Students at American Universities
• We Are the People Our Parents Warned Us Against
• Mississippi Notebook
• Two, Three, Many More (novel)
• Organized Crimes (novel)
• Citizen Cohn (1988)
• Capitalist Fools: Tales of American Business, from Carnegie to Forbes to the Milken Gang
• Hoax: Why Americans Are Suckered by White House Lies
• Geneva (play)
• Radical: A Portrait of Saul Alinsky (Nation Books, July 2010)