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Search - Preventing Alzheimer's Disease and Cognitive Decline

Preventing Alzheimer's Disease and Cognitive Decline
Author: National Institutes of Health

For many older adults, cognitive health and performance remain stable over the course of their lifetime, with only a gradual and slight decline in short-term memory and reaction times. But for others, this normal, age-related decline in cognitive function progresses into a more serious state of cognitive impairment or into various forms of de... more »mentia, including Alzheimer?s disease. Such loss of cognitive function?the ability to think, learn, remember, and reason?substantially interferes with everyday function. As researchers continue to explore changes in the brain that take place possibly decades before cognitive decline and dementia symptoms appear, they also hope to discover more about the relationship between normal age-related cognitive decline and the development of cognitive impairment or Alzheimer?s disease. Alzheimer?s disease was first described in 1906, when German psychiatrist and neuropathologist Alois Alzheimer observed the hallmarks of the disease in the brain of a female patient who had experienced memory loss, language problems, and unpredictable behavior: abnormal clumps of protein (now called beta-amyloid plaques) and tangled bundles of protein fibers (now called neurofibrillary tangles). Today, an estimated 2.5 to 4.5 million Americans are living with Alzheimer?s disease, the most common form of dementia, and those numbers are expected to grow with the aging of the baby-boomer population. Age is the strongest known risk factor for Alzheimer?s disease, with most people diagnosed with the late-onset form of the disease over age 60. An early-onset, familial form also occurs but is very rare. The time from diagnosis to death with Alzheimer?s disease ranges from as little as 3 years to 10 or more, depending on the person?s age, sex, and the presence of other health problems. In addition to investigating the causes and potential treatments for Alzheimer?s disease and other dementias, researchers are focused on finding ways to prevent cognitive decline. Many preventive measures for cognitive decline and for preventing Alzheimer?s disease?mental stimulation, exercise, and a variety of dietary supplements?have been suggested, but their value in delaying the onset and/or reducing the severity of decline or disease is unclear. Questions also remain as to how the presence of certain conditions, such as high cholesterol, high blood pressure, and diabetes, influence an individual?s risk of cognitive decline and Alzheimer?s disease. To examine these important questions about Alzheimer?s disease and cognitive decline in older people, the National Institute on Aging and Office of Medical Applications of Research of the National Institutes of Health will convene a State-of-the-Science Conference from April 26 to 28, 2010, to assess the available scientific evidence related to the following questions: What factors are associated with the reduction of risk of Alzheimer's disease? . What factors are associated with the reduction of risk of cognitive decline in older adults? . What are the therapeutic and adverse effects of interventions to delay the onset of Alzheimer's disease? Are there differences in outcomes among identifiable subgroups? . What are the therapeutic and adverse effects of interventions to improve or maintain cognitive ability or function? Are there differences in outcomes among identifiable subgroups?

ISBN-13: 9781495312168
ISBN-10: 149531216X
Publication Date: 1/24/2014
Pages: 132
Rating:

0 stars, based on 0 rating

Publisher: CreateSpace Independent Publishing Platform
Book Type: Paperback
Members Wishing: 0
Reviews: Amazon | Write a Review

Genres:

Health, Fitness & Dieting >> Mental Health >> Dementia
Medical Books >> Medicine >> Internal Medicine >> Neurology >> Alzheimer's Disease

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Search - Preventing Alzheimer's Disease and Cognitive Decline

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