Reports Author:Johns Hopkins Hospital Purchase of this book includes free trial access to www.million-books.com where you can read more than a million books for free. This is an OCR edition with typos. Excerpt from book: site which follows the completed segmentation." They note, as does Golgi, that the segmentation cannot be prevented if quinine be given when the parasite has rea... more »ched the preparatory stages. " Quinine acts on the amoeba of malaria," they say, " during those phases of its life in which it absorbs nourishment and develops; when the nutritive activity comes to an end, the transformation of haemoglobin into black pigment being accomplished, and the phase of reproduction begins, then quinine becomes inefficacious against this process." They agree with Golgi that to best combat the development of the infection/quinine should be in solution in the blood at the time of the setting free of the spores: i. e., it should be given several hours before the paroxysm. III.—GENERAL ANALYSIS OF 616 CASES OF MALAEIAL FEVEE. During the period between June 14th, 1889, and January 1st, 1894, 616 cases of malarial fever were observed in the wards and at the outpatient department of the Johns Hopkins Hospital. Of these, 333 were treated in the wards of the hospital, while 283 were treated at the out-patient department. Relapses of cases occurring in the hospital, treated later in the out-patient department, have not been counted in the list. Two of the 333 cases treated in the hospital were relapses of cases already on the list, and have therefore been left out in some of the tables. Of 614 cases in which the ages were obtained, there were: Between 1 and 10 years of age. 10 20 80 40 60 60 70 80 Total. 20 80 40 50 00 70 80 90 Relapses of cases treated in the out-patient department are not counted as new cases. Below is a table with the ages of 614 patients selected at random from the admissions to the hospital and the out-patient department— 331 from the hospital, and 283 fr...« less