Born in New Jersey in 1947, Weinberg sold his first story in 1967, and has been writing for the last few decades. Most of his writing career was conducted part-time while also owning a bookstore; he became a full time writer after 1997.

Weinberg is also an editor, and has edited books in the fields of horror, science fiction and western.

In comics, Weinberg has written for Marvel Comics; his first job was on the series Cable, and he later created the series Nightside starring Sydney Taine a character who had previously appeared in a short story Weinberg wrote.

Weinberg sits on the 'Council of Six', a board of editorial advisers for Canadian publisher Battered Silicon Dispatch Box. Along with another boardmember, George Vanderburgh, it has recently been announced that Weinberg will take the editorial reigns at Arkham House.

Anthologies edited

• Far Below and Other Horrors (1974)
• Pulp Classics 6 (1974)
• Revelry in Hell: Pulp Classics 3 (1974)
• Devils in the Dark (1979)
• 100 Tiny Terror Tales (1984) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• The Eighth Green Man and Other Strange Folk (1987)
• Weird Tales: 32 Unearthed Horrors (1988) (with Stefan R Dziemianowicz, Martin H. Greenberg)
• Mists From Beyond: 22 Ghost Stories and Tales from the Other Side (1989) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• 100 Fiendish Little Frightmares (1990) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Lovecraft's Legacy (1990) (with Martin H. Greenberg) Introduction by Robert Bloch
• Between Time and Terror (1990) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Rivals of Weird Tales (1990) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• A Taste for Blood (1991) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Famous Fantastic Mysteries (1991) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Hard-Boiled Detectives: 23 Great Stories from Dime Detective Magazine (1992) (with Stefan R. Dziemianowicz)
• 100 Ghastly Little Ghost Stories (1992) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Weird Vampire Tales (1992) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• To Sleep, Perchance to Dream...Nightmare (1993) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• 100 Dastardly Little Detective Stories (1993) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Nursery Crimes (1993) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Tough Guys and Dangerous Dames (1993)
• 100 Wild Little Weird Tales (1994) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• 100 Crooked Little Crime Stories (1994) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• 100 Creepy Little Creature Stories (1994) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• 100 Vicious Little Vampire Stories (1995) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• 100 Wicked Little Witch Stories (1995) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Great Writers and Kids Write Spooky Stories (1995) (with Martin H. Greenberg, Jill M. Morgan)
• 100 Astounding Little Alien Stories (1996) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Miskatonic University (1996) (with Martin H. Greenberg)
• 100 Tiny Tales of Terror (1996) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Rivals of Dracula (1996) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Virtuous Vampires (1996) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Girls' Night Out: 29 Female Vampire Stories (1997) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Mistresses of the Dark: 25 Macabre Tales by Master Storytellers (1998) (with Stefan R. Dziemianowicz, Denise Little)
• 100 Twisted Little Tales of Torment (1998) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• 100 Hilarious Little Howlers (1999) (with Stefan R. Dziemianowicz, Martin H. Greenberg)
• Dial Your Dreams: And Other Nightmares (2001)
• The Termination Node, Random House/Del Rey, science fiction novel, adult, 1999 hc/pb, co-author Lois H. Gresh
• The Computers of Star Trek, Basic Books, science, adult, 2000 hc/trade, ,co-author Lois H. Gresh
• The Science of Superheroes, John Wiley & Sons, science, adult, 2002 hc/trade, co-author Lois H. Gresh
• The Science of Supervillains, John Wiley & Sons, science, adult, 2004 hc/trade,co-author Lois H. Gresh
• The Science of James Bond, John Wiley & Sons, science, adult, 2006 trade, co-author Lois H. Gresh
• The Science of Anime, science, adult, 2005 trade, co-author Lois H. Gresh
• The Science of Stephen King, John Wiley & Sons, science, adult, 2007 hc, co-author Lois H. Gresh
• The Many Mysteries of Indiana Jones, John Wiley & Sons, science, adult (2008), trade, co-author Lois H. Gresh

Books Written

Masquerade of the Red Death Trilogy (1995) White Wolf PublishingThe Horizon War Trilogy (1996) White Wolf Publishing

Comics

Comics work includes:

• Nightside (with art by Thomas Derenick, 4-issue mini-series, Marvel Comics, 2002)