Rothchild grew up in Miami Beach, Florida and is one of three siblings. Her father, John Rothchild, is a well-known non-fiction writer and her mother, Susan Rothchild, is the daughter of famed New York City '21 Club' founder Charlie Berns. 

Rothchild attended Boston College and graduated with honors in 1998. She then moved to Los Angeles and began her writing career. She lives there now.

Rothchild was featured reading from her teen diary at the stage show, Mortified, on This American Life, My Experimental Phase episode. Her segment "Miami Vices" is on the This American Life best of CD, Hope and Fear. Rothchild was also featured on This American Life on Showtime, episode titled Growth Spurt.

Rothchild writes and produces reality television. She also writes scripted television, feature films and articles for various publications. She currently blogs about relationships for Psychology Today Magazine. Her LA Weekly article "How To Get Divorced By 30," about her failed starter marriage, spawned a memoir. How To Get Divorced By 30, published by Penguin, January 2010, is "an age-old story. Girl meets boy. Girly marries boy. Girl decides she is way too young to be stuck in nuptial mediocrity."