Long novel about a family in the rural Northeastern U.S. In the mid-eighteen fifties, a young woman who doesn't get along with her mother is sent for a long visit to her mother's school friend's home in an isolated area of Vermont. She later marries the woman's younger brother, a doctor. The family is wealthy, so medicine is more like a hobby for him. The main character accompanies him on his rounds, and they start and raise a family. Includes accounts on early photography, killer blizzards, and epidemics.

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