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Variability in Response to Anti-Rheumatic Drugs (Agents and Actions Supplements)
Variability in Response to AntiRheumatic Drugs - Agents and Actions Supplements Author:Peter Brooks, R. O. Day, Gerald G. Graham Therapy of rheumatiod arthritis is undergoing dramatic chamges. Greater appreciation of the long-term outcomes of this disease and the impacts of treatments has resulted in a more aggressive approach to therapy, especially in the early stages. An increasingly diverse array of anti-rheumatic drugs with novel effects on inflammation and the immune... more » system confronts us. One factor remains constant; individual response to anti-rheumatic therapy is highly variable, thus providing an important approach to understanding the heterogeneity of the disease process, as well as the mechanisms of drug action. Experts of international repute address in this volume relevant aspects of recent research into non-steroidal anti inflanunatory drugs, stereochemistry, pharmacodynamics and pharmacokinetics, trials and trial design, combination therapy, new and old disease-modifying anti-rheumatic drugs, adverse reactions, side effects. The result is a state-of-the-art review of anti-rheumatic drug therapy. Variability in Response to Anti-Rheumatic Drugs is a valuable source of information for rheumatic disease researchers and pharmacologists, rheumatologists, as well as general physicians and internists.« less