Once the world worked differently- before "the Silence" from space quieted the airwaves. Once there was a haven called Cresent City, built through the wonders of nanotechnology to transport its enlightened inhabitants into the cosmos. But humanity has failed the city. Dania Cooper and Jason Peabody, a recipient of the DNA-altering virus affecting a remarkable few who were born at the Silence's onset, now must flee the sentient metropolis- ambarking on a bizarre odyssey across a perilous, unrecognizable Earth. For a world that is not as it was is on the brink of yet another transformation- either by grand design or random cosmic accident.