Moore grew up in Virginia Beach, Virginia and attended Norfolk Academy. He majored in English at the University of Virginia, where he was an Echols Scholar, and later served as an intern in the White House for President Bill Clinton before starting his entertainment career in talent and development at MTV and VH1.

He worked as part of the original production team for The Rosie O'Donnell Show. Moore next worked as a development executive for the late filmmaker Ted Demme and producer Joel Stillerman before joining Walden Media, where he developed and oversaw such film projects as I Am David, the film adaptation of Anne Holm’s acclaimed novel North to Freedom.

Moore is openly gay and lives in New York City with Hunter Hill (a writer for Paper magazine).

Moore is also the executive producer of The Lion, the Witch and the Wardrobe. He was a longtime production executive for Walden Media, and was instrumental in bringing The Chronicles of Narnia series to the company. After landing the rights to the C. S. Lewis series, he moved into a production deal with the company. The film represents his first as a motion picture executive producer.

He continued his role as executive producer of Prince Caspian, released in 2008.

His most recent project is Lake City, a drama that tells the story of a mother (Sissy Spacek) and son (Troy Garity) who reunite under desperate circumstances years after a family tragedy drove them apart.

He is also co-directing a documentary about legendary children's book author and illustrator Maurice Sendak with partners Hunter Hill and filmmaker Spike Jonze.

In addition to his work in production and development, The C.S. Lewis Company appointed Moore to write The Chronicles of Narnia: The Lion, The Witch, and The Wardrobe: The Official Illustrated Movie Companion, a New York Times bestseller.

A longtime fan of children's literature and comic books, Moore's first novel, Hero, the first of a fantasy series about a group of modern-day superheroes, was published by Hyperion Books on August 28, 2007. The UK edition was published 8 May 2008. The young adult novel tells the story of the world's first gay teen superhero. In May 2008, Hero won a Lambda Literary Award as the best LGBT Children's/Young Adult novel of the past year. A television series is in the works with Stan Lee. In 2009, Moore began writing a sequel to Hero.