- Angry White Pyjamas: An Oxford Poet Trains With The Tokyo Riot Police (1998), a book recounting Twigger's experience as an uchi-deshi learning Aikido in Japan, won both the Somerset Maugham Award for literature and the William Hill Sports Book of the Year award. It was also voted best sports books of the past 25 years by Waterstone's booksellers in 2007.
- Big Snake: The Hunt for the World's Longest Python (1999) describes Twigger's failed attempt to capture a record-breaking 30-foot snake for a $50,000 prize being offered by a New York zoo.
- The Extinction Club (2001) is an account of Twigger's research into the Milu, a species of deer which was thought to have become extinct.
- Being a Man (in the lousy modern world) (2002) describes Twigger's thoughts and observations on the nature of masculinity and its current state at the beginning of the 21st century.
- Voyageur — Across the Rocky Mountains in a Birchbark Canoe (2006) recounts the story of Twigger's three-year, two thousand-mile journey across North West Canada in the wake of eighteenth-century explorer and trapper Alexander Mackenzie.
- Lost Oasis: A Desert Adventure: In Search Of Paradise (2007) is a desert adventure modelled on explorers such as Theodore Almasy (the inspiration for The English Patient).
- Real Men Eat Puffer Fish (2008) contains humorous advice for men.
- Dr Ragab's Universal Language (2009) is a novel set in 1920's Cairo and Germany.
Twigger has also published several poetry collections, including one in 2003 with Nobel Prize winner Doris Lessing.