He also received the [[Reuben Award#Elzie Segar Award|Elzie Segar Award]] in 1982 for his unique contribution to the cartooning profession. Keane was honored with the [[Reuben Award#Silver T-Square Award|Silver T-Square Award]] from the National Cartoonist Society in 2002 for "outstanding dedication" to the NCS and the cartooning profession.

• Keane had a close friendship with humorist, newspaper columnist, and fellow Catholic Erma Bombeck until her death in 1996. Keane provided illustrations for Bombeck's book Just Wait Until You Have Children of Your Own! (1972). Keane considers himself instrumental in convincing Bombeck to move to Arizona.
• Stephan Pastis, creator of Pearls Before Swine, acknowledged he is good friends with Keane and Keane's son, Jeff. Pastis has parodied The Family Circus in his own strip and Keane wrote a satirical attack as a foreword for Pastis' book Macho Macho Animals.
• The Keanes switched with Scott Adams of Dilbert in the infamous 1997 comic strip switcheroo.
• Keane has also counted fellow cartoonists Charles M. Schulz (Peanuts) and Jeff MacNelly (Shoe) as close friends.

Family Circus collections

Special compilations

• The Family Circus Treasury, foreword by Erma Bombeck (1977)
• The Family Circus Album, foreword by Charles Schulz (1984)
• The Family Circus is Us (1990)
• Family Circus Library, Vol. 1 (2009)
• Family Circus Library, Vol. 2 (2010)

Other cartoon collections

• Channel Chuckles (1964)
• Jest in Pun (1966)
• Pun-Abridged Dictionary (1968)
• More Channel Chuckles (1971)
• It's Apparent You're a Parent (1971)
• Deuce and Don'ts of Tennis (1975)
• Eggheads written by Bil Keane and Jeff Keane (1983)

Illustrated books

• Just Wait Till You Have Children of Your Own! written by Erma Bombeck and Bil Keane (1971)
• Hey, Father! written by Jeanne Marie Lortie, illustrated by Bil Keane (1973)
• Daddy’s Surprise Day written by Gale Wiersum, illustrated by Bil Keane (1980)
• Ask Any Mother written by Jean B. Boyce, illustrated by Bil Keane (1991)
• Just Ask Mom written by Jean B. Boyce, illustrated by Bil Keane (1996)
• Just Like Home written by Jean B. Boyce, illustrated by Bil Keane (2001)

• He is the father of Disney animator Glen Keane.
• Keane dropped the second "L" from his name as a teenager while working on a satire magazine with friends.
• He appears (as a cartoon character) in an episode of the animated series Pinky and the Brain as the face behind an investigator digging for dirt to overthrow Pinky's presidency.

• (about Peanuts cartoonist Charles Schulz): "I always said we had a lot in common: We both did a feature about kids and family values. He had five children; I had five children. He was born in 1922; I was born in 1922. He made a million dollars a week; I was born in 1922."