Powell has written and provided artwork for franchises of Dark Horse , DC Comics and Marvel , but is most regarded for his original series The Goon, which debuted from the small publisher Avatar Press. Powell quickly switched to self-publishing under the moniker Albatross Exploding Funny Books, before being picked up by Dark Horse after only a handful of issues. The Goon's quality was recognized with an Eisner Award in 2004 for Best Single Issue (Dark Horse The Goon #1) as well as an International Horror Guild award. The following year Powell won Eisner's Best Humor Publication and Best Continuing Series awards.
He is a featured interviewee in the movie Independents.
Conan #28 (with writer Kurt Busiek, Dark Horse, 2006)
The Dark Horse Book of the Dead (contributed the short story "The Wallace Expedition", TPB, Dark Horse, 2006, ISBN 1-59307-281-3)
The Goon:
Best Cellars #1 (1st Appearance Monster Boy by Eric Powell, Goon prototype)
Avatar Illustrated 1998 (Avatar Press)
Dreamwalker #0 (Avatar Press) (1st Appearance of The Goon, 4-page back-up story later reprinted in The Goon #1)
The Goon #1-3 (Avatar Press)
The Goon #1-32 (Dark Horse)
The Goon: Chinatown (Dark Horse, 2007, ISBN 1-59307-833-1)
The Goon: Fancy Pants Edition Volume 1 (limited edition hardcover collecting The Goon #1-2 (self published), #1,3,5,9 (Dark Horse Comics), Dark Horse, 2005, ISBN 1-59307-426-3)
The Goon: Fancy Pants Edition Volume 2: The Rise and Fall of the Diabolical Dr. Alloy (limited edition hardcover), Dark Horse, 2008, ISBN 1-59307-918-4)
The Goon: Rough Stuff (TPB collects The Goon #1-3 (Avatar Press), Dark Horse, 2004, ISBN 1-59307-086-1)
The Goon Volume 1: Nothin' But Misery (TPB collects The Goon #1-4, The Goon Color Special (self published) , Dark Horse, 2003, ISBN 1-56971-998-5)
The Goon Volume 2: My Murderous Childhood (and Other Grievous Yarns) (TPB collects The Goon #1-4, Dark Horse, 2004, ISBN 1-59307-109-4)
The Goon Volume 3: Heaps Of Ruination (TPB collects The Goon #5-8, Dark Horse, 2005, ISBN 1-59307-292-9)
The Goon Volume 4: Virtue and the Grim Consequences Thereof (TPB collects The Goon #9-13, Dark Horse, 2006, ISBN 1-59307-456-5)
The Goon Volume 5: Wicked Inclinations (TPB collects The Goon #14-18, Dark Horse, 2006, ISBN 1-59307-646-0)
The Goon Volume 6: Chinatown (Dark Horse, 2007, ISBN 1-59307-833-1)
The Goon Volume 7: A Place of Heartache and Grief (TPB collects The Goon #19-23, Dark Horse, 2009, ISBN 1-59582-311-5)
The Goon Volume 8: Those That is Damned (TPB collects The Goon #24-27, Dark Horse, 2009, ISBN 1-59582-324-7)
The Goon Volume 9: Calamity of Conscience (TPB collects The Goon #28-31, Dark Horse, 2009, ISBN 1-59582-346-8)
Superman: Escape from Bizarro World (with writers Geoff Johns and Richard Donner, TPB collects "Action Comics" #855-857, DC Comics, 2007, ISBN 1140121794)
Books Illustrated
Billy Hooten: Owlboy (with author Thomas E. Sniegoski, published by Yearling Books, 2008, ISBN 978-0-440-42180-1)
Covers
Living Hell #1-6 (DC Comics)
Billy the Kid's Old-Timey Oddities #1-4 (Dark Horse Comics)
Billy the Kid's Old-Timey Oddities trade collection (Dark Horse Comics)
Freddy vs. Jason vs. Ash (DC Comics)
Think Like a Machine #1-2 (Dark Horse Comics))
Think Like a Machine trade collection (Dark Horse Comics)
