Ono was born in Nakatsu, ?ita, Ky?sh? in 1960. She graduated from ?tani University in Ky?to with a degree in Buddhist Studies, and in 1988 was employed by the publisher K?dansha. Her debut story is titled .

Ono is married to , a mystery novelist who writes under the pseudonym .

Before she started work on Twelve Kingdoms, Fuyumi Ono wrote , a horror novel about a boy from another world. She later worked certain events from this novel into the Twelve Kingdoms series. Short stories set in the various kingdoms include: , , , and . In February, 2008, the first new Twelve Kingdoms short story, Hisho no Tori (????) was published in Shinchosha's Yomyom magazine.

According to an interview at the Anime News Network, she is "currently rewriting a girls’ horror series (she) wrote long ago."

Novels

• Can't Sleep on Birthday Eve (?????????????) 1988 Kodansha
• Mephisto and Waltz! (?????????!) 1988 Kodansha ISBN 978-4061902497, Continuation of Can't Sleep on Birthday Eve
• Evil Spirits Aren't Scary (??????????) 1989 Kodansha ISBN 978-4061902572
• Evil Spirit Series (?????? - Akury? series) Kodansha
• There are lots of Evil Spirits?! (???????!?) 1989 ISBN 978-4061903111
• There are really lots of Evil Spirits! (???????????!) 1989 ISBN 978-4061903654
• Too many Evil Spirits to sleep (????????????) 1990 ISBN 978-4061904170
• A lonely Evil Spirit (?????????) 1990 ISBN 978-4061904859
• I Don't Want to Become an Evil Spirit! (?????????!) 1991 ISBN 978-4061905948
• Don't Call me an Evil Spirit (????????) 1991 ISBN 978-4061985759
• I don't mind Evil Spirits 1 (????????!???) 1992 ISBN 978-4061986961
• I don't mind Evil Spirits 2 (????????!???) 1992 ISBN 978-4061986978
• Charmed 17 year old (????17?) 1990 ??????
• 17 Springs Passed (??????? Sugiru J?shichi no Haru)1995 Kodansha ISBN 978-4062552011, an adaptation of Charmed 17 year old
• Green Home Spirits (????????????) 1990????????
• Home, Green Home (????? Home?Green Home) 1997 Kodansha ISBN 978-4062552943?an adaptation of Green Home Spirits
• Demon's Child (?????Mash? no Ko) 1991 Shinchosha ISBN 4-10-124021-3 Loosely associated with the 12 Kingdom Series
• Twelve Kingdoms Series (????) Kodansha unless otherwise noted
• Shadow of the Moon, Sea of the Shadow (??? ???) 1992 ISBN 4-06-255071-7 US Publication: 3/2007 Tokyo Pop ISBN 1598169467 as Sea of Shadow
• Sea of the Wind, Shore of the Labyrinth (??? ????) 1993 ISBN 4-06-255114-4 as Sea of Wind
• Sea God of the East, Vast Sea of the West (???? ????) 1994 ISBN 4-06-255168-3
• A Thousand Miles of Wind, the Sky of Dawn (???? ????) 1994 ISBN 4-06-255175-6
• Aspired Wings (????) 1996 ISBN 4-06-255229-9
• Drifting Ship (??) 1997 (short story)
• Shore at Dusk, Sky at Dawn (???? ???) 2001 ISBN 4-06-255546-8
• Kashou's Dream (?????) 2001 ISBN 4-06-255573-5
• Prosperity in Winter (??) originally published 4/2001 IN?POCKET
• Kashou (??) originally published 5/2001 Mephisto
• Jougatsu (??)
• Correspondence (??)
• Kizan (??)
• London, 1888 (???1888) 10/1993 Logout
• Strange T?kei Tales (???? - T?kei Ibun) (runner up for the 1993 Japan Fantasy Novel Award) 1994 Shinchosha ISBN 978-4101240220
• Ghost Hunt Series (????????????) A continuation of the Evil Spirit Series, but in a different setting
• Nightmare Dwelling 1 (??????(?)) 1994 Kodansha ISBN 978-4062551564
• Nightmare Dwelling 2 (??????(?)) 1994 Kodansha ISBN 978-4062551649
• Shiki (??, literally Corpse Demon) 1998 Shinchosha ISBN 978-4103970026
• Island of the Black Shrine (????) 2001 Shodensha ISBN 978-4396331641
• Kura no Kami (?????) 2003 Kodansha ISBN 978-4062705646
• Ghost Stories Storybook (????) Serialized since June, 2000 in the magazine Yuu