Sturges is best known for the Eisner-award nominated Jack of Fables from DC/Vertigo. In the 1990s, he was a member of the writers' collective Clockwork Storybook, which also included Bill Willingham, Chris Roberson, and Mark Finn.

With Willingham Sturges has not only worked on Fables but has also co-written House of Mystery. Following his signing an exclusive deal with DC Comics, Sturges took over the writing of Blue Beetle in issue #29 and will see it through to its end in issue #36. He has also written Final Crisis Aftermath: Run! featuring the Human Flame and, with Willingham again, he is also taking over the writing of Justice Society of America with issue #29.

He is also the author of a novel, Midwinter (2009), and a book of short horror fiction, Beneath the Skin and Other Stories (2000).

He currently lives in Pflugerville, Texas.

Comics work include:

• Jack of Fables #1- (with co-author Bill Willingham, Vertigo, September 2006—present)
• Shadowpact #17-25 (DC Comics, September 2007 - July 2008)
• Countdown to Mystery: "A Syzygy in Plastic" #1-8 (DC Comics, November 2007 - June 2008)
• Salvation Run #3-7 (DC Comics, March - July 2008)
• House of Mystery #1- (with co-author Bill Willingham, Vertigo, July 2008—present) collected as:
• Room and Boredom (collects House of Mystery #1-5, 128 pages, January 2009, ISBN 1-40122-079-7)
• Blue Beetle #29-36 (with artist Rafael Albuquerque, DC Comics, September 2008 - April 2009)
• Final Crisis Aftermath: Run! (with Freddie Williams, DC Comics, 6-issue limited series, 2009, forthcoming)

Interviews

• Inside the Comic Writer's Studio interview, Comicbloc.com, September, 2007
• Sequential Tart interview, September 2006
• Behind the Page - Matthew Sturges, Part 1, Newsarama, February 5, 2009